1. High blood pressure
   
   
2. Protein and/or blood in the urine
   
   
3. Creatinine and BUN blood tests outside the normal range*
   
   
4. Glomerular filtration rate (GFR) of less than 90**
   
   
5. More frequent urination, particularly at night; difficult or painful urination
   
   
6. Puffiness around eyes, swelling of hands and feet
   
   

* BUN and creatinine are wastes that build up in the blood when your kidney function is reduced.

** GFR (a measure of kidney function) is estimated from a blood creatinine test. In some people, a GFR of 60 to 89 may be normal.

Updated: 05/14/04

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See also in this A-Z guide:

• Interstitial Cystitis
• Urinary Tract Infections

All health information in this A-Z Guide has been approved for medical accuracy by the Scientific Advisory Board of the National Kidney Foundation. This information was current as of the date listed at the top of the page. Our Scientific Advisory Board members.

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©2006 National Kidney Foundation. All rights reserved. This material does not constitute medical advice. It is intended for informational purposes only. No one associated with the National Kidney Foundation will answer medical questions via e-mail. Please consult a physician for specific treatment recommendations.